Can garlic help with antibiotic resistance?

Scientists hope that they have solved the increasing threat of human antibiotic resistance by reproducing a substance found in garlic.

The compound ajoene was made in a laboratory for the first time, and hopes that it can now be manufactured at a low price and on a large scale.

Antibiotic resistance has been labeled by medical professionals as one of the most urgent threats to public health.

They fear that an increase in drug-resistant superbeest can become a reality caused by excessive use of antibiotics.

Antibiotics resistance occurs when bacteria develop the ability to defeat the drugs that are designed to kill them.

But the new findings could help combat the threat after ajoene, a colorless liquid that interferes with the chemical communication signals between bacteria, is made synthetic for the first time.

The results of the research led by Cardiff University are published in the leading chemistry magazine Angewandte Chemie.

Lead author of the study Professor Thomas Wirth, from the School of Chemistry at Cardiff University, said: "With the help of readily available raw materials, we have successfully created an efficient, robust and reliable way to produce ajoene in large volumes.

"The remarkable antibacterial properties of this compound have shown great promise and we hope that this new breakthrough will speed up efforts to produce ajoene in large quantities and better test its effectiveness as a therapeutic drug."

Australian Associated Press

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