Serbian midfielder Nemanja Matic and Ecuadorian full-back Antonio Valencia have to play this season, while Chilean Alexis Sanchez missed the loss of Sunday at Brighton & Hove Albion.
All three are back on the training field, together with the Portuguese follower Diogo Dalot, who underwent surgery just before the club closed in the late season.
Mourinho said he was not sure which of these players would play against Spurs.
"I do not know because today it is still Friday and we are training on Saturday and Sunday, and the race is on Monday", he said.
"Decisions have to be taken on Sunday, but yes, they are training with the team, Dalot is also training with the team for the first time this week, so in the medical department they are almost free," he added.
Mourinho was far from expansive in his answers to questions from the press about the situation at the club and their form so far.
"I feel like we played well against Leicester (City) and we won, I feel we played badly against Brighton and we lost," he said, adding that he hoped against Tottenham his team: " would play well and win, would not make mistakes, play well and win, that's what we want. "
Mourinho ignored questions about media criticism from him and his team, saying that he read less than 10 percent of what was written in newspapers and the same for television.
"I'm not the right person to answer," he said, and he had the same amount of guts when asked to evaluate the central defenders Eric Bailly and Victor Lindelof's performances.
"I do not analyze my players together with you," he added.
The former manager of Chelsea and Real Madrid bluntly denied any break with the director of the club, Ed Woodward, and refused to comment on the midfielder Paul Pogba's statement that he and the team's stance were not correct in the 3-2. demise in Brighton.
"Paul has to answer his words: if you want any explanation about Paul's words, you must take him and ask him," Mourinho said.
(Reporting by Simon Evans; Editor by Christian Radnedge)