Deep wrinkles in the forehead indicate cardiovascular disease



Are there many wrinkles on the forehead worrying?

As people grow older, more and more wrinkles develop on the skin over time. Researchers now discovered that deep forehead wrinkles can also be an early sign of cardiovascular disease.

Researchers from the Center Hospitalier Universitaire de Toulouse, France, discovered in their recent research that deep forehead wrinkles can indicate the development of cardiovascular disease. The doctors presented the results of their current study at the congress of the European Association for Cardiology (ESC) in Munich.

The development of wrinkles is a natural process, because the skin becomes thinner and drier with years. However, researchers have now discovered that many deep wrinkles on the forehead may also indicate an increased risk of cardiovascular disease. (Image: Syda Productions / fotolia.com)

Excessive wrinkles can be associated with arteriosclerosis

If people have more forehead wrinkles than is normal for people of their age, this may indicate an increased risk of dying from the effects of cardiovascular disease, experts say. Excess wrinkles can be associated with atherosclerosis, hardening of the arteries due to plaque buildup, the researchers add. Atherosclerosis is a major cause of heart attacks and other cardiovascular problems.

Do the blood vessels on the forehead speak on plaque deposits?

Changes in the collagen protein that gives structure to our hair, skin and nails and oxidative stress seem to play a role in both atherosclerosis and wrinkles. The study suggested that the small blood vessels in the forehead may be more sensitive to plaque deposits, which means that wrinkles may be a sign of aging of the blood vessels. The scientists analyzed a group of 3,200 adults for their study. All participants were healthy and 32, 42, 52 or 62 years old.

Depth and number of wrinkles were scored on a scale

Subjects were assigned scores depending on the number and depth of the wrinkles on their foreheads. A value of zero meant no wrinkles, a value of three meant many deep wrinkles. The participants were medically assisted for a period of 20 years. During this time, 233 subjects died from various causes. At the end of the study, 15.2 percent had a wrinkle score of two or three, 6.6 percent had a score of one and 2.1 percent had a score on the wrinkle scale of zero, say the authors of the study. The researchers discovered that people with a wrinkle value of one had a slightly higher risk of dying from cardiovascular disease than people without wrinkles.

For some people the risk was almost ten times higher

People with a wrinkle number of two and three had an almost ten times greater risk of premature death compared to people without wrinkles. This increased risk persisted after correction for factors such as age, gender, education, smoking status, blood pressure, heart rate, diabetes and lipid levels.

Forehead wrinkles are an easily identifiable visual marker

The higher the value of the fold, the greater the risk of cardiovascular mortality, says study author Professor Yolande Esquirol of the Center Hospitalier Universitaire de Toulouse. The forehead wrinkles were examined as markers because they are easily visually detectable. Just looking at the face of a person can indicate an increased risk, then experts can respond and give advice to reduce the risk, adds the author. Advice can include direct lifestyle changes such as more exercise or a healthier diet.

A healthy lifestyle reduces the risk of heart disease

The risk of heart disease increases with age, but a healthy lifestyle and medical interventions can reduce the risk. The challenge is to identify high-risk patients early enough to make a difference, the doctors explain.

Further studies are needed

If you are a person with a possible cardiovascular risk, you should have checked classic risk factors such as blood pressure and fat and blood sugar levels, Esquirol adds. This is the first time that an association between cardiovascular risk and forehead wrinkles has been established. The results must now be assessed in further studies. (Ash)



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