Why elephants do not get cancer




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Elephants; & # 10 can not cancer ill & # 8211; Reason for this is his own gene, such as scientists from the University of Chicago now discovered. The rare gene LIF6, also known as the zombie gene, protects the animals against the often dormant disease, as the doctors write in the diary Cell reports Write.

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Also with elephants it is about cancerous mutations. However, the gene controls it: it attacks cells that are about to mutate in cancer cells. Other animals also have the LIF gene, but usually it is not functional or dead. elephants But apparently they have found a way to reactivate the gene. For that reason, the researchers called the gene "Zombie Gen".

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defense system

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In laboratory experiments they discovered that the possibly dormant mutations in elephant cells disappeared. The immune system of the gray giant is activated by the presence of LIF6. When scientists blocked the gene scientifically, the damaged cells survived and were also & # 10;cancerWhen the gene was introduced into animals that were normally absent, for example in men, they were also immune to it cancer,

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The gene produces a protein that drills holes in the mitochondria. This will automatically kill the damaged cells. This programmed suicide is called apoptosis.

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Transferable for people?

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The question that arises from the research is whether the ability of it elephants can also be transferred to people. It may be possible to develop medicines that improve the behavior of the LIF6 elephants imitate.

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Other animals also have a natural resistance cancer developed. These include, for example, bats, whales and slugs.

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elephants can not cancer The reason is his own gene, as scientists of the University of Chicago now discovered. The rare gene LIF6, also known as the zombie gene, protects the animals against the often deadly disease, such as the doctors in the diary Cell reports Write.

Also with elephants it is about cancerous mutations. The gene, however, combats this: it attacks cells that are about to mutate into cancer cells. Other animals have the LIF gene, but it is usually not functional or dead. elephants But apparently they have found a way to reactivate the gene. For this reason, the researchers called the gene "zombie gene".

defense system

In laboratory experiments they discovered that the potentially deadly mutations in elephant cells disappeared. The immune system of the gray giant is activated by the presence of LIF6. When the scientists artificially blocked the gene, the damaged cells survived and were closed
cancer
When the gene was introduced in animals that were normally absent, such as in mice, they were also immune to it cancer,

The gene produces a protein that drills holes in the mitochondria. This will automatically kill the damaged cells. This programmed suicide is called apoptosis.

Transferable for people?

The question that arises from the research is whether the ability of it elephants can also be transferred to people. Drugs may be developed that contribute to the behavior of the LIF6 elephants imitate.

Other animals also have a natural resistance to it cancer developed. These include bats, whales and slugs.


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