Pfizer vaccine protects cancer patients and other immunocompromised patients against pneumococcal pneumonia – Jornal Dia Dia



Patients with clinical conditions affecting the immune system, such as cancer and HIV, as well as those who have undergone a transplant, are at increased risk of presenting pneumonia and invasive pneumococcal disease in comparison. with healthy individuals1.2. In the world pneumonia is a major cause of hospitalization and deaths. And in Brazil, the disease did not lead to the intake of 163,286 people in hospitals connected to the Unified Health System (SUS) until the first four months of 2018.

In HIV carriers, the decrease in the ability of the defense cells caused by the virus causes the patient to present a risk of contracting pneumonia up to 100 times greater in relation to people without this condition.3. "In the case of oncological patients, the immune system can be weakened by the disease and also by treatments based on chemotherapy or radiotherapy, which also affect the immune cells", says specialist in infectious diseases Cláudia Murta of Santa Casa de Belo Horizonte.

The use of immunosuppressive drugs, given to prevent rejection in transplant patients, also interferes with the immune system. In the case of bone marrow transplantation, including, the patient must be re-immunized because the procedure clears their immune memory.

pneumonia
Pneumonia is a disease of the airways caused by bacteria, viruses or fungi. And three out of ten diagnosed cases have been associated with pneumococcal bacteria4. That is why vaccination against this drug is of great importance, especially for risk patients, and is well established in the vaccination schemes of Brazil and the world.

One of the vaccines that can immunize these patients against pneumococcal pneumonia is Prevenar 13 from Pfizer, which provides protection against pneumonia caused by the 13 most common pneumococcal serotypes worldwide: 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F. It is also the only pneumococcal conjugate vaccine with a license for all ages in Brazil.

References

  1. PELTON YES et al. Rates of pneumonia in children and adults with chronic medical conditions Germany. BMC infection Dis. 2015; 15 (1): 470.
  2. WELTE T and all Clinical and economic burden of community acquired pneumonia in adults Europe. Thorax. 2012; 67 (1): 71-9.
  3. ORTQVIST A et al. Streptococcus pneumoniae: epidemiology, risk factors and clinical features. Semin Respir Crit Care Med. 2005; 26 (6): 563-74.
  4. WELTE T et al. chest, part 67 (1), page & # 39; s 71-79, 2012.

SOURCE Pfizer


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