Obese teenagers may be at risk of pancreatic cancer

If your teen or young adult child is obese, he or she may be four times greater than the risk of developing pancreatic cancer later in life, warns new research.

Researchers from the University of Tel Aviv analyzed 1,087,358 Jewish men and 707,212 women between 16 and 19 years of age for the study published in the journal CANCER.

It showed that overweight and even a higher weight within the "normal" weight range in men can increase pancreatic cancer risk in a graded manner.

In comparison with normal weight, obesity was associated with 3.76 times higher cancer risk in men and a 4.07 times higher risk in women, the report said.

In addition, high-normal BMI and overweight men were associated with 49 percent and 97 percent higher risk of cancer, respectively, compared with patients with low normal BMI.

Pancreatic cancer is the sixth most common cause of cancer deaths in the world and adult obesity has been associated with an increased risk for its occurrence.

It has an extremely low survival rate that has hardly improved in the past 40 years.

The combination of complex chemical, biological, bio-mechanical and structural factors found in pancreatic cancer tissues makes it difficult to treat.

Systemic inflammation caused by obesity is a potential motor behind the development of pancreatic cancer. Managing the weight can thus help reduce the risk, the researchers noted.

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