A two-year American girl who needs different blood transfusions to fight cancer has launched a global campaign to look for compatible donors.
Zainab Mughal has one of the rarest blood groups in the world, making it difficult to treat her condition.
Campaigners say that more than 1,000 people have been tested, but only three so far have the blood they need.
According to doctors, seven to ten donors are needed in the course of her cancer treatment.
Earlier this year, Zainab was diagnosed with neuroblastoma, an aggressive and rare form of cancer that occurs mainly in babies and young children.
Blood transfusions are necessary for the duration of her treatment, but Zainab's blood is "extremely rare" because it lacks an antigen – "Indian B" – that most people have in their red blood cells, says OneBlood, a non-profit blood center that the pivot is the search for donors.
The only donors likely to be matched are people of Pakistani, Indian or Iranian origin, and with blood group O or A, says OneBlood.
But even within these countries, less than 4% of the population will miss the Indian B antigen.
The body of Zainab will reject any blood that does not meet all requirements.
"This is so rare that I honestly saw this the first time I've done this in the last 20 years", says Frieda Bright, laboratory manager at OneBlood.
OneBlood collaborates with other blood banks and the American Rare Donor Program (ARDP), a program that finds donors of rare types of blood around the world.
Two matching donors were found in the US and another in the UK.
"Blood is not going to cure her, but it's very important for her to survive cancer treatment," Bright said in campaign video.
& We've cried a lot & # 39;
Zainab's father Raheel Mughal said his daughter was diagnosed in October.
"We were all crying, this was the worst we expected," he said in a OneBlood video.
After he and the mother of Zainab tried to donate their own blood, doctors discovered that neither was compatible.
"And then many people from my family, they went around and donated blood and that is when it became more of a warning."
According to OneBlood, treatment with chemotherapy is already reducing the size of the tumor, but ultimately Zainab needs two bone marrow transplants.
"The life of my daughter is very dependent on the blood," says Mr. Mughal.
"What [donors] to save my daughter's life is great. I will never forget the work you do. "