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Tumors, discovered in broccoli, a deadly weapon to eliminate them



Tumors, discovered in broccoli, a deadly weapon to eliminate them

in Broccoli and in other similar vegetables there is a protein that can become part of the weapons cancer: indeed a study led by the Italian Pier Paolo Pandolfi, director of the Cancer Center and Cancer Research Institute at the Beth Israel Deaconess Medical Center in Boston, shows that a natural compound (indole-3-carbinol) is present in the & # 39; crucifers & # 39; (the broccoli family, which also includes cauliflower, turnip greens, etc.) switches off a gene that promotes tumors. The discovery is reported in the journal Science.

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"We have discovered an important new actor that contains the ranks of a critical cancer development mechanism, an enzyme called WWP-1 that can be eliminated by a natural compound found in broccoli and other vegetables» – said Pandolfi. "This mechanism therefore reveals itself as an achilles heel that can become the target of new therapeutic options». In animal studies susceptible to the development of different cancers, the experts discovered that a molecule known to suppress the development of tumors (PTEN, called oncosuppressor) is deactivated by WWP-1 and beaten by striking WWP-1 with indol-3-carbinol de PTEN function is restored and tumor growth suppressed. Of course this is still a preliminary study, but indol-3-carbinol suggests the basis for developing new anti-cancer therapies. Last update: 5:14 PM


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