American researchers have investigated the criteria that led to the development of autoimmune diseases. Vitamin D therefore appeared to be an important factor in maintaining health, it was his lack that caused such serious diseases.
This sends Chronicle Info with reference to medikforum.ru.
A team of scientists from the United States spoke about new factors in the emergence of a number of serious illnesses related to reduced immunity. The publication Frontiers in Immunology published an article about the University of Edinburgh research staff on the effect of vitamins on autoimmune diseases. Vitamin D therefore influences human immunity, which increases the chance of resistance to health threats. A shortage of this element weakens the body and makes it more susceptible to a number of diseases, such as multiple sclerosis.
In adults, vitamin D deficiency can cause osteomalacia, making the bones softer. This is due to the reduced ability of dendritic cells to activate T cells. In children, vitamin deficiency leads to rickets, whereby bone tissue can be deformed. In addition, experts from the University of Utah also investigated the situation with colleagues. They created specific immunotoxins that are able to effectively kill cells with the presence of a defective PD-1 protein.
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Scientists studied gene mutations that provoke the development of immune responses to tissues and organs in the body. The developed immunotoxin contains antibodies against PD-1, exotoxin produced by Pseudomonas bacteria and albumin, the binding domain. Experiments with rodents have demonstrated the effectiveness of the vitamin in blocking the development of the disease. Vitamin D is produced in the body under the influence of sunlight, while it ensures the absorption of phosphorus and calcium in the small intestine. Vitamin D deficiency is one of the most important risk factors for autoimmune diseases.
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