Sandalwood that mimics sandalwood could stimulate hair growth in humans



A chemical that mimics sandalwood has shown that it has the ability to stimulate hair growth in people find a new study. This brings hope for people who lose hair worldwide.

Researchers at the Monasterium Laboratory, Münster, have expressed the hope that this new chemical could effectively treat hair loss and try to test the drug for its effectiveness on human volunteers. Professor Ralf Paus, a scientist at the University of Manchester who led the research, called this an "astonishing finding." He said that this widely used fragrance that is used cosmetically in many products has been seen for the first time to be a "normal" human mini organ. [a hair]. "The team discovered that there was a chemical pathway in the hair follicles affected by this substance, which promoted hair growth and also delayed the death of the follicles." The results of the study appeared in the latest issue of the journal. Nature Communications.

The chemical in question is Sandalore. The chemical is used to make perfumes and soaps to reproduce the smell of sandalwood. The team noticed that this fragrance stimulates chemical cells in the nose. The team discovered that not only cells in the nasal passages stimulate these chemicals also other cells in the body, such as hair follicles.

Red sandal wood. Image credits: Rifad / Shutterstock

Red sandal wood. Image credits: Rifad / Shutterstock

They noted that there is a receptor called OR2AT4 that can be stimulated by Sandalore. This receptor was found in the outer layers of the hair follicles. They explain that the hair follicle receptors are able to 'smell' the chemical & # 39; with their special receptors. When applied over the outer scalp tissues, Sandalore could reduce hair fall or follicular death and stimulate new hair growth. The results were clinically significant, the researchers say.

This study was sponsored by a company in Italy – Giuliani Pharma S.p.A., which provides Sandalore with a cosmetic product to stimulate her, said Pope. Scalp tissues were taken for this study from patients undergoing face lift surgery. The tissues were exposed to Sandalore or to a rose-like scent Phenirat. Phenirat is known as an OR2AT4 blocker. Within 6 days, hair growth was observed in the tissues exposed to Sandalore. Pope explained that this was followed by a "very small, short and preliminary clinical pilot study" with only 20 female volunteers who were given Sandalore on their scalp. Larger clinical trials are expected to start next year, Pope said.

Source:

https://www.nature.com/articles/s41467-018-05973-0


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