Fever on the forehead can lead to heart disease along the line

In the 20-year study, which was presented at the European Society of Cardiology Congress in Munich, a group of more than 3,200 participants were assigned scores, depending on the number and depth of the wrinkles on their foreheads.

A zero score meant no wrinkles, while three & # 39; numerous deep wrinkles & # 39; meanings.

Of the 233 participants who died during the two decades, 15.2 percent scored two and three, 6.6 percent had scored one and 2.1 percent had no wrinkles.

Researchers found that people with wrinkle scores of two or three were almost 10 times more likely to die compared to those with zero wrinkle scores, after adjustments for other health factors.

Study author Dr. Yolande Esquirol, associate professor of occupational health at the Center Hospitalier Universitaire de Toulouse in France, said: "The higher your wrinkle score, the more your cardiovascular mortality risk rises.

"You can not see or feel risk factors such as high cholesterol or hypertension.We have examined wrinkles on the forehead as a marker because it is so simple and visual."

The link between wrinkles and cardiovascular disease is thought to be due to changes in collagen protein and oxidative stress – an imbalance between free radicals and antioxidants in the body – that play a role in both the formation of wrinkles and the build-up of plaque. in blood vessels.

The latter, known as atherosclerosis, contributes significantly to heart attacks and other cardiovascular events.

Blood vessels in the forehead can be particularly sensitive to plaque building due to their small size, which means that a grooved forehead can be an early sign of aging of the blood vessel.

While such wrinkles – played by actors George Clooney, Mel Gibson and Tom Hardy along with chef Gordon – are not a better way to evaluate the risk of CVD than blood pressure tests or lipid profiles, Dr. Esquirol said they could lift an early red flag.

"Looking at the face of a person alone could be an alarm, then we could give advice to reduce the risk," she said.

"This is the first time a link has been made between cardiovascular risk and forehead wrinkles, so the findings should be confirmed in future studies, but practice could now be used in doctors' offices and clinics.

"It costs nothing and there is no risk."

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