Two drugs in one pill to transform the blood pressure treatment!



It turns out that a single pill with two drugs has the ability to change the treatment of a patient with fluctuating blood pressure.

A recent study by the European Society of Cardiology has confirmed this.

The study confirmed that an important reason for poor blood pressure control is that patients do not take their pills. Non-adherence increases with the number of pills, so administering two drugs (or three if necessary) in a single tablet could change the blood pressure controls.

Previously, doctors advised a step-by-step treatment, which meant starting with one medication and then adding a second or third if necessary. This resulted only in "trauma of the doctor", where doctors are reluctant to change the initial strategy despite the lack of success.

Researchers claim that at least 80% of patients should have had an upgrade to two drugs, but most remained at one.

"The vast majority of patients with high blood pressure should start treatment with two drugs as a single pill, these pills are already available and should greatly improve the success of the treatment, with corresponding reductions in strokes, heart disease and early deaths, "said lead researcher, Professor Bryan Williams.

More than a billion people worldwide have hypertension. Approximately 30-45% of adults are affected and more than 60% of them are older than 60 years.

High blood pressure is the leading cause of premature death worldwide, accounting for almost ten million deaths in 2015, of which 4.9 million were due to ischemic heart disease and 3.5 million to stroke.

High blood pressure usually does not cause symptoms, but people with very high blood pressure can have headaches, blurred or double vision, regular nosebleed, trouble breathing, chest pain, irregular heartbeat, blood in the urine, confusion or knocking in the chest, neck or ears.

Researchers recommend that people suffering from the above symptoms should have it checked by a doctor immediately.

"Many more millions of people, especially in the older age groups, should be treated for high blood pressure." If you are 65 to 80 years old and your blood pressure is higher than 140/90 mmHg, you should be at risk of stroke and heart disease. reduce, "Williams added.

It is increasingly recognized that vulnerability, independence and biological, rather than chronological, age determine the tolerability and the likely benefit of blood-pressure-lowering medication. For people over 80 years of age, who have not yet received blood pressure treatment, therapy should be performed if the systolic blood pressure is 160 mmHg or higher, according to the study.

Researchers have even recommended that people who are already taking medication should not retire at the age of 80 if it is well tolerated.

Systolic blood pressure ranging from 120 -129 mmHg for patients younger than 65 years and 130-139 mmHg for patients older than 65 years should be treated immediately. Blood pressure below 120 mmHg should not be the target for any patient, because the risk of damage is greater than the potential benefits.

When blood pressure is not controlled by three drugs given in a single pill, a condition known as resistant hypertension, a second pill with a diuretic such as spironolactone should be added. Device-based therapy is not recommended for the routine treatment of these patients and should only be administered during clinical trials.

The doctors recommend a healthy lifestyle for all patients, regardless of the blood pressure level, because this can slow down the need for medication or supplement its effects. The advice includes salt restriction, alcohol sobriety, healthy eating, regular exercise, weight control, smoking cessation and a new recommendation to prevent alcohol abuse.

The study appears in the European Heart Journal. (ANI)


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